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PHILADELPHIA CHROMOSOME
Descriptors Found:
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DeCS
Descriptor
English
:
Philadelphia Chromosome
Descriptor
Spanish
:
Cromosoma Filadelfia
Descriptor
Portuguese
:
Cromossomo Filadélfia
Synonyms
English
:
Ph1 Chromosome
Tree Number:
A11.284.187.520.300.325.345.500
A11.284.187.520.300.505.515.500
C23.550.210.870.680
G13.920.590.175.870.680
G14.162.520.300.325.345.700
G14.162.520.300.505.515.700
Definition
English
:
An aberrant form of human CHROMOSOME 22 characterized by translocation of genetic material from chromosome 22, usually to the long arms of chromosome 9. It is present in the
bone marrow cells
of 80 to 90 per cent of
patients
with chronic myelocytic
leukemia
(LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).
See Related
English
:
Oncogene Proteins, Fusion
History Note
English
:
86; was see CHROMOSOMES, HUMAN, 21-22 1978-85
Record Number:
19631
Unique Identifier:
D010677
Occurrence in VHL
:
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